WebTwo checkpoint inhibitors, e.g. antibodies against programmed cell death protein 1 (PD-1), are currently FDA approved for second-line therapy of recurrent and/or metastatic head … WebJun 5, 2024 · In a retrospective study of 9 patients with recurrent and/or metastatic head and neck squamous cell carcinoma (RM-HNSCC) treated between December 2015 and January 2024, two patients [ages and sexes not stated] were described, of whom one patient developed acute kidney injury, and other patient developed anaphylaxis during …
KEYNOTE-048: A Phase III Study of First-Line Pembrolizumab for ...
WebFirst-line treatment of metastatic or unresectable recurrent head and neck squamous cell carcinoma (HNSCC) as monotherapy, in adult patients whose tumours have PD-L1 expression [Combined Positive Score (CPS) ≥ 1] as determined by a validated test. First-line treatment of metastatic or unresectable recurrent head and neck squamous cell ... WebApr 5, 2024 · Currently, standard treatment for endometrial cancer is chemotherapy alone. But adding pembrolizumab to a chemotherapy regimen improved progression-free survival in patients with advanced or recurrent endometrial cancer, according to results from a phase 3 trial that included 816 patients.. Patients with the deficient mismatch repair form of … phillip fulmer record
BEMPEG With Pembrolizumab vs Pembrolizumab Alone in Patients …
WebOct 11, 2024 · PURPOSE Pembrolizumab and pembrolizumab-chemotherapy demonstrated efficacy in recurrent/metastatic head and neck squamous cell carcinoma in KEYNOTE-048. Post hoc analysis of long-term efficacy and progression-free survival on next-line therapy (PFS2) is presented. METHODS Patients were randomly assigned … WebMay 22, 2024 · In recurrent/metastatic (R/M) squamous cell carcinoma of the head and neck (HNSCC), nivolumab and pembrolizumab were approved in 2016 for the … WebApr 14, 2024 · Abstract. Background: Single agent pembrolizumab in relapsed/metastatic head and neck squamous cell carcinoma (R/M HNSCC) has an ORR of 19% and mOS … phillip fulmer house